1. Tsai KL* ,Hung CH, Chan SH, Hsieh PL, Ou HC, Cheng YH, Chu PM (2018, Jun). Chlorogenic Acid Protects Against oxLDL-Induced Oxidative Damage and Mitochondrial Dysfunction by Modulating SIRT1 in Endothelial Cells.. Molecular Nutrition & Food Research, 62(11):e1700928.

2. Chen HY, Lin LT, Wang ML, Tsai KL*,Huang PI, Yang YP, Lee YY, Chen YW, Lo WL, Lan YT, Chiou SH, Lin CM, Ma HI, Chen MT. (2018, May). Musashi-1 promotes chemoresistant granule formation by PKR/eIF2α signalling cascade in refractory glioblastoma.. Biochim Biophys Acta Mol Basis Dis. 1864(5 Pt A):1850-1861. .

3. Ma CH, Chiua YC, Wu CH, Jou IM, Tu YK, Hung CH, Hsieh PL, Tsai KL*,(2018, May). Homocysteine causes dysfunction of chondrocytes and oxidative stress through repression of SIRT1/AMPK pathway: A possible link between hyperhomocysteinemia and osteoarthritis.. Redox Biology, 15:504-512. (＊correspondence author).

4. Chan SH, Hung CH, Shih JY, Chu PM, Cheng YH, Lin HC, Hsieh PL, Tsai KL*,(2018, Apr). Exercise intervention attenuates hyperhomocysteinemia-induced aortic endothelial oxidative injury by regulating SIRT1 through mitigating NADPH oxidase/LOX-1 signaling.. Redox Biology, 14:116-125. (＊correspondence author).

5. Zhu GC, Tsai KL* ,Cgen YW, Hung CH (2018, Apr). Neural Mobilization Attenuates Mechanical Allodynia and Decreases Proinflammatory Cytokine Concentrations in Rats With Painful Diabetic Neuropathy. Physical Therapy, 1;98(4):214-222.

6. Ma CH, Wu CH, Jou IM, Tu YK, Hung CH, Hsieh PL, Tsai KL*. (2018, Apr). PKR activation causes inflammation and MMP-13 secretion in human degenerated articular chondrocytes.. Redox Biology , 14:72-81. (＊correspondence author).

7. Ma CH, Chiu YC, Tsai KL*,Tu YK, Yen CY, Wu CH. (2017, Dec). Masquelet technique with external locking plate for recalcitrant distal tibial nonunion.. Injury, 48(12):2847-2852..

8. Cheng YH, Chavez E, Tsai KL*,Yang KC, Kuo WT, Yang YP, Chiou SH, Lin FH. (2017, Oct). Effects of thermosensitive chitosan-gelatin based hydrogel containing glutathione on Cisd2-deficient chondrocytes under oxidative stress.. Carbohydrate Polymers , 173:17-27.

9. Chan SH, Hung CH, Shih JY, Chu PM, Cheng YH, Lin HC, Tsai KL* , (2017, Jun). SIRT1 inhibition causes oxidative stress and inflammation in patients with coronary artery disease. Redox Biology , 2;13:301-309. MOST 105-2311-B-006-008. (＊correspondence author).

10. Tsai KL* ,Huang PC, Chen YW, Lin HT, Hung CH. (2017, Jun). Exercise Combined With Ultrasound Attenuates Neuropathic Pain in Rats Associated With Downregulation of IL-6 and TNF-α, but With Upregulation of IL-10. Anesthesia & Analgesia , 124(6):2038-2044. (＊correspondence author).

11. Tsai KL* ,Kao CL, Hung CH, Cheng YH, Lin HC, Chu PM. (2017, May). Chicoric acid is a potent anti-atherosclerotic ingredient by anti-oxidant action and anti-inflammation capacity. Oncotarget, 8:29600-29612. MOST 105-2311-B-006-008.

12. Tsai KL* , Huang PC, Wang LK, Hung CH, Chen YW. (2017, Mar). Incline treadmill exercise suppresses pain hypersensitivity associated with the modulation of pro-inflammatory cytokines and anti-inflammatory cytokine in rats with peripheral nerve injury.. Neuroscience Letters, 16;643:27-31.

13. Chan SH, Chu PM, Kao CL, Cheng YH, Hung CH, Tsai KL* ,(2016, Oct). Oleic acid activates MMPs up-regulation through SIRT1/PPAR-γ inhibition: a probable linkage between obesity and coronary arterial disease.. J Biochem. , 160(4):217-225. (＊correspondence author).

14. Tsai KL*,Hung CH, Chan SH, Shih JY, Cheng YH, Tsai YJ, Lin HC, Chu PM (2016, Oct). Baicalein protects against oxLDL-caused oxidative stress and inflammation by modulation of AMPK- alpha. Oncotarget, Vol. 7, No. 45,72458-72468. MOST 103-2320-B-006-050.

15. Chan SH, Hung CH, Shih JY, Chu PM, Cheng YH, Tsai YJ, Lin HC, Tsai KL* ,(2016, Jun). Baicalein is an available anti-atherosclerotic compound through modulation of nitric oxide-related mechanism under oxLDL exposure. Oncotarget, 7(28),42881-42891. MOST 103-2320-B-006-050. (＊correspondence author).

16. Cheng YH, Tsai TH, Jhan YY, Chiu AW, Tsai KL* ,Chien CS, Chiou SH, Liu CJ. (2016, Jun). Thermosensitive chitosan-based hydrogel as a topical ocular drug delivery system of latanoprost for glaucoma treatment.. Carbohydr Polym.

17. Tsai KL* , Wang CT, Kuo CH, Cheng YY, Ma HI, Hung CH, Tsai YJ, Kao CL. (2016, May). The potential role of epigenetic modulations in BPPV maneuver exercises.. Oncotarget., 7(24):35522-35534.

18. Hung CH, Chan SH, Chu PM, Lin HC, Tsai KL* ,(2016, Mar). Metformin regulates oxLDL-facilitated endothelial dysfunction by modulation of SIRT1 through repressing LOX-1-modulated oxidative signaling. Oncotarget, 7(10):10773-87. MOST 103-2320-B-006-050. (＊correspondence author).

19. Hung CH, Chan SH, Chu PM, Lin HC, Tsai KL* ,(2016, Mar). Metformin regulates oxLDL-facilitated endothelial dysfunction by modulation of SIRT1 through repressing LOX-1-modulated oxidative signaling. Oncotarget, 7(10):10773-87. MOST 103-2320-B-006-050. (＊correspondence author).

20. Hung CH, Chan SH, Chu PM, and Tsai KL* ,(2015, Oct). Quercetin is a potent anti-atherosclerotic compound by activation of SIRT1 signaling under oxLDL stimulation.. Molecular Nutrition & Food Research , 59(10):1905-17. (＊correspondence author).

21. Cheng YY, Kao CL, Ma HI , Hung CH, Wang CT, Liu DH, Chen PY, and Tsai KL* ,(2015, Oct). SIRT1-related inhibition of pro-inflammatory responses and oxidative stress are involved in the mechanism of nonspecific low back pain relief after exercise through modulation of Toll-like receptor 4.. The Journal of Biochemistry , 158(4):299-308.. (＊correspondence author).

22. Tsai KL* ,Cheng YY, Leu HB, Lee YY, Chen TJ, Liu DH, Kao CL. (2015, Sep). Investigating the role of Sirt1-modulated oxidative stress in relation to benign paroxysmal positional vertigo and Parkinson's disease.. Neurobiology of Aging, 36(9):2607-16.

23. Hung CH, Chan SH, Chu PM, and Tsai KL* . (2015, Jun). Homocysteine facilitates LOX-1 activation and endothelial death through the PKCβ and SIRT1/HSF1 mechanism: relevance to human Hyperhomocysteinemia.. Clinical Science, 129 (6) 477-487. (＊correspondence author).

24. Hung CH, Chan SH, Chu PM, and Tsai KL* . (2015, May). Docetaxel Facilitates Endothelial Dysfunction through Oxidative Stress via Modulation of Protein Kinase C Beta: The Protective Effects of Sotrastaurin.. Toxicological Sciences , 145(1):59-67. (＊correspondence author).

25. Tsai KL* , Chang YL, Huang PH, Cheng YH, Liu DH, Chen HY, Kao CL. (2014, Aug). Ginkgo biloba extract inhibits oxidized low-density lipoprotein (oxLDL)-induced matrix metalloproteinase activation by the modulation of the lectin-like oxLDL receptor 1-regulated signaling pathway in human umbilical vein endothelial cells.. Journal of Vascular Surgery.

26. Tsai KL* , Kao CL, Cheng YY, Kuo CH, Lee SD and Chan RC. (2014, Mar). Vestibular rehabilitation ameliorates chronic dizziness through the SIRT1 axis. Frontiers in Aging Neuroscience , 6:27.. (＊correspondence author).

27. Tsai KL* , Huang PH, Kao CL, Leu SB, Cheng YH, Liao YW, Yang YP, Chien Y, Wang CY, Hsiao CY, Chiou SH, Chen JW, Lin SJ. (2014, Mar). Aspirin attenuates Vinorelbine-induced endothelial inflammation via modulating SIRT1/AMPK axis . Biochemical Pharmacology, 15;88(2):189-200.

28. Ou HC, Hsieh YL, Yang NC, Tsai KL* , Chen KL, Tsai CS, Chen IJ, Wu BT, Lee SD. (2013, Jan). Ginkgo biloba extract attenuates oxLDL-induced endothelial dysfunction via an AMPK-dependent mechanism. Journal od Applied Physiology , 114(2):274-85.

29. Tsai KL* , Huang YH, Kao CL, Yang DM, Lee HC, Chou HY, Chen YC, Chiou GY, Chen LH, Yang YP, Chiu TH, Tsai CS, Ou HC, Chiou SH. (2012, May). A novel mechanism of coenzyme Q10 protects against human endothelial cells from oxidative stress-induced injury by modulating NO-related pathways. The Journal of nutritional biochemistry, May;23(5):458-68.. (SCI).

30. Tsai KL* , Chiu TH, Tsai MH, Chen HY, and Ou HC. (2012, Apr). Vinorelbine-induced oxidative injury in human endothelial cells mediated by AMPK/PKC/NADPH/NF-κB pathways.. Cell biochemistry and biophysics, Apr;62(3):467-79.. (SCI).

31. Tsai KL* , Chen LH, Chiou SH, Chiou GY, Chen YC, Chou HY, Chen LK, Chen HY, Chiu TH, Tsai CS, Ou HC, Kao CL. (2011, Sep). Coenzyme Q10 suppresses oxLDL-induced endothelial oxidative injuries by the modulation of LOX-1-mediated ROS generation via the AMPK/PKC/NADPH oxidase signaling pathway. Molecular nutrition and food research, Sep;55 Suppl 2:S227-40. (SCI).

32. Kuo MY, Ou HC, Lee WJ, Kuo WW, Hwang LL, Song TY, Huang CY, Chiu TH, Tsai KL* , Tsai CS, Sheu WH-H. (2011, May). Ellagic acid inhibits oxidized low-density lipoprotein (OxLDL)-induced metalloproteinase (MMP) expression by modulating the protein kinase C-α/extracellular signal-regulated kinase/peroxisome proliferator-activated receptor γ/nuclear factor-κB (PKC-α/ERK/PPAR-γ/NF-κB) signaling pathway in endothelial cells. Journal of agricultural and food chemistry, May 11;59(9):5100-8. (SCI).

33. Chen LH, Tsai KL* , Chen YW, Yu CC, Chang KW, Chiou SH, Ku HH, Chu PY, Tseng LM, Huang PI, Lo WL. (2011, Feb). MicroRNA as a Novel Modulator in Head and Neck Squamous Carcinoma.. Journal of Oncology. (SCI).

34. Lee WJ, Ou HC, Hsu WC, Chou MM, Tseng JJ, Hsu SL, Tsai KL* , Hsu WC, Sheu WH* (2010, Oct). Ellagic acid protects endothelial cells from oxidized low-density lipoprotein-induced apoptosis by modulating the PI3K/Akt/eNOS pathway. TOXICOLOGY AND APPLIED PHARMACOLOGY, 248卷 ( 2期)： 134頁 ～ 143頁 . (SCI). NSC 98-2320-B-039-020-my3.

35. Ou HC, Song TY, Yeh YC, Huang CY, Yang SF, Chiu TH, Tsai KL* , Chen KL, Wu YJ, Tsai CS, Chang LY, Kuo WW, Lee SD*. (2010, Jun). EGCG protects against oxidized LDL-induced endothelial dysfunction by inhibiting LOX-1-mediated signaling.. JOURNAL OF APPLIED PHYSIOLOGY, 108卷 (6 期)：1745 頁 ～1756 頁 . (SCI). NSC 98-2320-B-039-029-my3.

36. Lee WJ, Ou HC, Wu CM, Lee IT, Lin SY, Lin LY, Tsai KL* , Lee SD, Sheu WH* (2009, Dec). Sesamin mitigates inflammation and oxidative stress in endothelial cells exposed to oxidized low-density lipoprotein. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 57卷 ( 23期)： 11406頁 ～11417 頁 . (SCI). NSC 98-2320-B-039-020-my3.

37. Kuo WW, Huang CY, Chung JG, Yang SF, Tsai KL* , Chiu TH, Lee SD*, Ou HC*. (2009, Apr). Crude Extracts of Solanum lyratum Protect Endothelial Cells Against Oxidized Low-Density Lipoprotein-Induced Injury Via Direct Antioxidant Action. JOURNAL OF VASCULAR SURGERY, 50卷 (4 期)： 849頁 ～860 頁 . (SCI). NSC 97-2314-B-39-003.

38. Ou HC, Lee WJ, Lee IT, Chiu TH, Tsai KL* , Lin CY, Sheu WH*. (2006, May). Ginkgo biloba extract attenuates oxLDL-induced oxidative functional damages in endothelial cells.. Journal of Appylied Physiology, 105卷 ( 5期)：1674 頁 ～ 1685頁 . (SCI). NSC 96-2320-B-039-040.

39. Hung CH, Kao CL ,Chan SH , Tsai KL* . Exercise training reduces chronic dizziness by inhibiting NADPH oxidase. Standard Scientific Research and Essays Vol. 2(12), pp. 626-631 December 2014

40. Hung CH, Chan SH, Chu PM, Tsai KL* . 2015 Docetaxel Facilitates Endothelial Dysfunction through Oxidative Stress via Modulation of Protein Kinase C Beta: The Protective Effects of Sotrastaurin. Toxicol Sci. 145(1):59-67. (SCI)

41. Cheng YT, Kao CL, Ma HI, Hung CH, Wang CT ,Liu DH, Chen PY, Tsai KL* . 2015. SIRT1-related inhibition of pro-inflammatory responses and oxidative stress are involved in the mechanism of nonspecific low back pain relief after exercise through modulation of Toll-like receptor 4. Journal of Biochemistry 2015:1-10. (SCI)

42. Hung CH, Chan SH, Chu PM, Tsai KL* . 2015. Homocysteine facilitates LOX-1 activation and endothelial death through the PKCβ and SIRT1/HSF1 mechanism: relevance to human Hyperhomocysteinemia. Clin Sci (Lond). 129(6):477-487. (SCI)

43. Tsai KL , Cheng YY, Leu HB, Lee YY, Chen TJ, Liu DH, Kao CL. 2015. Investigating the role of Sirt1-modulated oxidative stress in relation to Benign Paroxysmal Positional Vertigo and Parkison's Disease. Neurobiology of Aging. 36(9):2607-2616. (SCI)

44. Hung CH, Chan SH, Chu PM, Tsai KL* . 2015. Quercetin is a potent anti-atherosclerotic compound by activation of SIRT1 signaling under oxLDL stimulation. Molecular Nutrition & Food Research. 0:1-13. (SCI)

45. Tsai KL , Chang YL, Huang PH, Cheng YH, Liu DH, Chen HY, Kao CL. Ginkgo biloba extract inhibits oxidized low-density lipoprotein (oxLDL)-induced matrix metalloproteinase activation by the modulation of Q1 the lectin-like oxLDL receptor 1-regulated signaling pathway in human umbilical vein endothelial cells. Journal of Vascular Surgery accepted.

46. Kao CL, Tsai KL, Cheng YY, Kuo CH,Lee SD, Chan RC. Vestibular rehabilitation ameliorates chronic dizziness through the SIRT1 axis. Front Aging Neurosci. 2014 Mar 4;6:27.

47. Tsai KL, Huang PH, Kao CL, Leu SB, Cheng YH, Liao YW, Yang YP, Chien Y, Wang CY, Hsiao CY, Chiou SH, Chen JW,Lin SL. Aspirin attenuates Vinorelbine-induced endothelial inflammation via modulating SIRT1/AMPK axis. Biochem Pharmacol. 2013 in press (IF=4.576,Q1, 29/261, JCA=3X5X5=75)

48. Ou HC, Hsieh YL, Yang NC, Tsai KL, Chen KL, Tsai CS, Chen IJ, Wu BT, Lee SD. Ginkgo biloba extract attenuates oxLDL-induced endothelial dysfunction via an AMPK-dependent mechanism. J Appl Physiol. 2013 Jan 15;114(2):274-85.

49. Tsai KL, Chiu TH, Tsai MH, Chen HY, Ou HC. Vinorelbine-induced oxidative injury in human endothelial cells mediated by AMPK/PKC/NADPH/NF-κB pathways. Cell Biochem Biophys. 2012 Apr;62(3):467-79. (IF=3.734, Q1, 18/74, JCA=3X5X5=75)

50. Tsai KL, Chen LH, Chiou SH, Chiou GY, Chen YC, Chou HY, Chen LK, Chen HY, Chiu TH, Tsai CS, Ou HC, Kao CL. Coenzyme Q10 suppresses oxLDL-induced endothelial oxidative injuries by the modulation of LOX-1-mediated ROS generation via the AMPK/PKC/NADPH oxidase signaling pathway. Mol Nutr Food Res. 2011 Sep;55 Suppl 2:S227-40. (IF=4.301, Q1, 2/128, JCA=3X5X5=75)

51. Tsai KL, Huang YH, Kao CL, Yang DM, Lee HC, Chou HY, Chen YC, Chiou GY, Chen LH, Yang YP, Chiu TH, Tsai CS, Ou HC, Chiou SH. A novel mechanism of coenzyme Q10 protects against human endothelial cells from oxidative stress-induced injury by modulating NO-related pathways. J Nutr Biochem. 2012 May;23(5):458-68. Epub 2011 Jun 17. (IF=4.552, Q1, 8/72, JCA=3X5X5=75)

52. Tsai KL, Chen LH, Vhen YC, Kao CL, Chen LK, Chiou SH. The role of microRNAs in modulating sirtuin 1 expression. Journal of Clinical Gerontology & Geriatrics .2011 Spt Volume 2, Issue 3 , Pages 71-75

53. Chen LH, Tsai KL, Chen YW, Yu CC, Chang KW, Chiou SH, Ku HH, Chu PY, Tseng LM, Huang PI, Lo WL. MicroRNA as a Novel Modulator in Head and Neck SquamousCarcinoma. Journal of Oncology. 2010:135632. Epub 2011 Feb 15. (Co-First  author)

54. Chen YC, Tsai KL, Hung CW, Ding DC, Chen LH, Chang YL, Chen LK, Chiou SH. Induced pluripotent stem cells and regenerative medicine. Journal of Clinical Gerontology & Geriatrics. 2011.Mar Volume 2, Issue 1 , Pages 1-6 (Co-First  author)

55. Kuo MY, Ou HC, Lee WJ, Kuo WW, Hwang LL, Song TY, Huang CY, Chiu TH, Tsai KL, Tsai CS, Sheu WH. Ellagic acid inhibits oxidized low-density lipoprotein (OxLDL)-induced metalloproteinase (MMP) expression by modulating the protein kinase C-α/extracellular signal-regulated kinase/peroxisome proliferator-activated receptor γ/nuclear factor-κB (PKC-α/ERK/PPAR-γ/NF-κB) signaling pathway in endothelial cells. J Agric Food Chem. 2011 May 11;59(9):5100-8. Epub 2011 Apr 11.

56. Lee WJ, Ou HC, Hsu WC, Chou MM, Tseng JJ, Hsu SL, Tsai KL, Sheu WH. Ellagic acid inhibits oxidized LDL-mediated LOX-1 expression, ROS generation, and inflammation in human endothelial cells. J Vasc Surg. 2010 Nov;52(5):1290-300. Epub 2010 Aug 8.

57. Ou HC, Lee WJ, Lee SD, Huang CY, Chiu TH, Tsai KL, Hsu WC, Sheu WH. Ellagic acid protects endothelial cells from oxidized low-density lipoprotein-induced apoptosis by modulating the PI3K/Akt/eNOS pathway. Toxicol Appl Pharmacol. 2010 Oct 15;248(2):134-43. Epub 2010 Aug 4.

58. Ou HC, Song TY, Yeh YC, Huang CY, Yang SF, Chiu TH, Tsai KL, Chen KL, Wu YJ, Tsai CS, Chang LY, Kuo WW, Lee SD. EGCG protects against oxidized LDL-induced endothelial dysfunction by inhibiting LOX-1-mediated signaling. J Appl Physiol. 2010 Jun;108(6):1745-56. Epub 2010 Mar 4.

59. Lee WJ, Ou HC, Wu CM, Lee IT, Lin SY, Lin LY, Tsai KL, Lee SD, Sheu WH. Sesamin mitigates inflammation and oxidative stress in endothelial cells exposed to oxidized low-density lipoprotein. J Agric Food Chem. 2009 Dec 9;57(23):11406-17.

60. Kuo WW, Huang CY, Chung JG, Yang SF, Tsai KL, Chiu TH, Lee SD, Ou HC. Crude extracts of Solanum lyratum protect endothelial cells against oxidized low-density lipoprotein-induced injury by direct antioxidant action. J Vasc Surg. 2009 Oct;50(4):849-60. Epub 2009 Aug 22.

61. Ou HC, Lee WJ, Lee IT, Chiu TH, Tsai KL, Lin CY, Sheu WH. Ginkgo biloba extract attenuates oxLDL-induced oxidative functional damages in endothelial cells. J Appl Physiol. 2009 May;106(5):1674-85. Epub 2009 Feb 19.

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1. 2008年Society for Heart and Vascular Metabolism國際研究會，第一作者海報發表，美國麻薩諸塞州。Green tea epigallocatechin-3-gallate (EGCG) reduced endothelial cells dysfunction and adhesion molecule expression induced by oxidized-LDL。

2. 2008年Society for Heart and Vascular Metabolism國際研究會，第二作者海報發表，美國麻薩諸塞州。Ginkgo biloba extract inhibits oxidized LDL-induced cytotoxicity in endothelial cells。

3. 2008年Society for Heart and Vascular Metabolism國際研究會，第二作者海報發表，美國麻薩諸塞州。Protective effects of solanum lyratum thunb on oxidized LDL-induced cytotoxicity in endothelial cells。

4. 2009年生物醫學聯合學術年會，第一作者口頭發表，台北。(-)Epigallocatechin-3-gallate (EGCG), a Polyphenolic Compound in Green Tea, Protetcs Against Endothelial Cells Inflammation via Oxidized LDL。

5. 2009年The American College of Sports Medicine國際研究會，第一作者海報發表，美國華盛頓州。Solanum Lyratum Thumb Prevent Oxidized Low-density Lipoprotein-induced Endothelial Dysfunction。Supported by NSC

6. 2009年The American College of Sports Medicine國際研究會，第四作者海報發表，美國華盛頓州。Attenuation of inflammation in (-)epigallocatechin-3-gallate(EGCG) -treated endothelial cells via oxidized LDL。

7. 2010年The Experimental Biology 2010國際研究會，第二作者海報發表，美國加州。EGCG protects against oxLDL-induced endothelial dysfunction by inhibiting LOX-1-mediated signaling。

8. 2010年8th Annual Scientific Sessions: Metabolic Signaling in the Cardiovascular System國際研究會，第二作者海報發表，加拿大Inhibitory effect of coenzyme Q10 on endothelial apoptosis induced byoxidized low oxidized low-density lipoprotein via inhibiting ROS/P38MAPK/NF kappaBpathway。

9. 2011年The Experimental Biology 2011國際研究會，第一作者海報發表，美國華盛頓特區。A novel mechanism of Coenzyme Q10 protects against human endothelial cells from oxidative stress-induced by modulating NO-related pathways。

10. 2012年Mechanism-Based Natural Product Development Conference，第一作者海報發表，加拿大溫哥華。Ginkgo biloba extract attenuates oxLDL-induced endothelial dysfunction via an AMPK-dependent mechanism。Supported by NSC

11. 2013年MipTec2013 - The Leading European Event for Drug Discovery，第一作者海報發表，瑞士巴塞爾。Aspirin mitigates Vinorelbine-facilitated endothelial inflammation via modulating SIRT1/LKB1/AMPK mechanism。

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