This laboratory was established in 2005. Our research interest is in the effects of exercise or clinical administration on respiratory and circulatory system in diseases (such as diabetes mellitus) and its underlying mechanisms. Many experimental methods are used to monitor the changes of cardiopulmonary functions and cardiovascular parameters after exercise training in patient populations, including exercise pulmonary function test, ultrasonic transit-time flowprobe, hemodynamic signal monitor/analysis, blood gas, enzyme-linked immnunosorbent assay, measurements of lung injury and edema. In addition, we also determine the pathological changes about diabetic neuropathy by analgesia equipments. We try to find out the benefits and mechanisms of exercise intervention, hence we could provide a new theory on physical therapy and clinical applications. Hope to offer the important information for the clinical therapists.

The present research is to disclose the effects of exercise training on diabetes mellitus by combining clinical research and experimental animal model:

A. Clinical research

We cooperate with Chi Mei Medical Center to assess the benefits of exercise training in diabetic patients, and its improvements in respiratory and cardiovascular system. 

B. Animal's experiment

Because of the limitations of human study, we use the animal model of diabetes mellitus in order to determine the effect of exercise training on respiratory system, circulatory system, central nerve system, and peripheral nerve system and the underlying mechanisms in diabetic rats. It also recognized that does exercise training increase the beneficial proteins inside, decrease inflammatory response and damages, and then prevent complications in diabetes.